Headache, nausea and vomiting during menstruation are mainly due to vaginal bleeding caused by the shedding of the uterine lining during menstruation. When the endometrium is shedding, a certain amount of prostaglandins will be released. Due to individual differences, the degree of sensitivity to prostaglandins varies, and the amount of prostaglandins released also varies. Individuals who are more sensitive to prostaglandins may experience headaches, nausea and vomiting due to the contraction of vascular smooth muscle and gastrointestinal smooth muscle caused by prostaglandins, as well as contraction of uterine smooth muscle, and may also experience pain in the lower abdomen due to the secretion of prostaglandins. It is recommended to give proper rest during menstruation and take oral vitamin B6 to relieve gastrointestinal symptoms and oral vitamin B1 to nourish the nerves to relieve headache.