In the clinical urine protein (+) need to pay attention to the hospital to improve the relevant examination to clarify the causes of urine protein: First, physiological factors can lead to urine protein, such as after strenuous exercise or fever, will lead to a transient increase in protein urine, generally rest for a period of time or fever temperature down to normal, protein urine can return to normal. Second, primary kidney disease, such as glomerular disease, common clinical glomerulonephritis will lead to increased urine protein, and renal tubular disease will lead to reduced protein urine reabsorption, so the urine inside the urine protein will increase. Third, secondary kidney disease factors, such as systemic lupus erythematosus, hepatitis B or C-associated nephritis, and multiple myeloma will lead to an increase in urine protein.