Neurodermatitis, the purpose of treatment is mainly to stop itching, mainly including general treatment, topical drug treatment, oral drug treatment and so on. 1. General treatment: It is recommended to reduce and remove the triggering factors, avoid the use of irritating cosmetics, skin care products, do not use hot water, avoid scratching and friction, but also pay attention to the skin’s moisturizing, to prevent the skin from being too dry. At the same time, psychological counseling should be carried out to relieve stress, anxiety and irritability and other negative emotions. 2. Topical medication: Commonly used topical medications include tacrolimus ointment, pimecrolimus cream, mometasone furoate cream, etc., which can inhibit the local inflammatory reaction and relieve symptoms. 3. Oral drug treatment: neurodermatitis causes obvious itching sensation, antihistamines can be given, such as ibastine, loratadine, etc., which can help relieve itching symptoms. Some patients may be triggered by psychological and mental factors, and if necessary, eszopiclone tablets and doxepin tablets can be given to treat the corresponding diseases, which can better relieve the symptoms. Severe neurodermatitis is treated by intravenous closure with procaine if necessary. Patients diagnosed with neurodermatitis are advised to go to the dermatology department of the hospital in time, and standardize the treatment under the guidance of the doctor.