Drinking alcohol after taking cephalosporin will produce a disulfiram-like reaction, mild facial flushing, rapid heartbeat, severe nausea, dyspnea, drop in blood pressure and even shock life-threatening. Drinking alcohol after taking cephalosporin, cephalosporin will affect the liver’s metabolism of alcohol, inhibit the enzyme of acetaldehyde dehydrogenase in the liver, so that alcohol in the oxidation of acetaldehyde can not continue to oxidize, thus causing acetaldehyde in the body to a large number of accumulation, and a series of reactions, that is, the bisulphuric reaction. Disulfiram-like reaction can be manifested as rapid heartbeat, excessive sweating, facial flushing, dizziness and so on. In severe cases, chest tightness, chest pain, nausea and vomiting, dyspnea, drop in blood pressure, and even loss of consciousness and life-threatening shock. Therefore, it is forbidden to take drinks containing alcohol 3 days before taking Cephalosporin, during and 7 days after taking the medicine to avoid the occurrence of disulfiram-like reaction. Cephalosporin should be used in accordance with medical advice.