HPV (human papillomavirus) type 16 positive, usually easy to turn negative, there are a few patients do not easily turn negative. 1. Easy-to-convert cases: If there are no other chronic diseases and the immune function is normal, most of the patients can be converted to HPV on their own after infection without special treatment, pay attention to hygiene, and have regular checkups. 2. In cases where the infection is not easily reversible: for example, if the patient has chronic diseases or is taking immunosuppressants, or if the patient has defective immune function or poor physical condition, the infection may not be easily reversible. If it causes pre-cancerous cervical lesions, timely cervical conization is needed; if the persistent infection does not turn negative on its own, further treatment should be carried out and more physical exercise should be done to improve the immune system. If you are positive for HPV type 16, you should seek medical advice and follow the doctor’s instructions.