The spiritual and psychological care of cancer patients cannot be ignored and is very important. When patients are diagnosed with rectal cancer, they will inevitably have two different mentality, one is fear, indignation, multiple criticism, and they can’t get along with themselves, which leads to patients’ rebellion when they need warmth the most, and they worry about themselves all day long, which makes the disease worse; the other is to adopt the attitude of “if you are here, you can rest in peace”, not to complain about God and others. The other one is to take the “as it comes, so be it”, not to blame God, can seriously and correctly treat the disease, usually can get the understanding and sympathy of medical staff, family and friends and others. Practice has proved that the prognosis of two states of mind, strong will to live and optimistic spirit and depressed and broken spirit, is very different. For rectal cancer patients, because of the slow development of rectal cancer, if early detection and early and reasonable surgical treatment, most of them can obtain satisfactory results, and the survival period is more than 5 years, 10 years or even 20 years. There is a spiritual psychological care factor here. To build up the confidence to overcome the disease and mobilize the body’s anti-cancer ability through reasonable protection and conditioning, the prognosis will be satisfactory if the will to live is enhanced. If you are sad, pessimistic, depressed and lose confidence in the disease all day long, you will deplete the positive energy of the human body, and as a result, the cancer does not succumb to the disease, but the internal environment of the human body is changed due to the role of the spirit, and the qi and blood are out of order and the essence is decayed in advance. Therefore, rectal cancer patients are hereby cautioned to pay attention to spiritual care, to keep their spirits intact, to follow the doctor’s orders and to actively cooperate with the treatment, believing that they can definitely overcome cancer and obtain a good prognosis.