Hiccups are also known as hiccups. Frequent hiccups may be caused by physiological factors such as eating too fast, eating stimulating foods, etc., but if there are other uncomfortable symptoms may be related to pathological factors such as gastrointestinal diseases, craniocerebral diseases and other diseases. 1. Dietary factors: such as eating too fast, eating too much, eating stimulating foods such as chili peppers, ginger, etc. can cause diaphragmatic spasm, hiccups and other symptoms. The symptoms can be relieved by deep breathing and distraction. 2. Gastritis: Gastritis can cause hiccups, acid reflux, heartburn and other symptoms. 3. Reflux esophagitis (GERD): GERD can cause hiccups as well as retrosternal pain and nausea. 4. Craniocerebral diseases: including intracranial infection, intracranial tumor, cerebrovascular disease, etc., which leads to frequent hiccups due to the stimulation of diaphragm and phrenic nerve. Frequent hiccups should first clarify the cause of the disease, such as prolonged non-relief should go to the regular hospital for a clear diagnosis, targeted treatment.