There is a certain probability that hepatitis E will heal on its own, but patients with acute hepatitis E can also suffer from liver damage and can experience a range of symptoms such as nausea, vomiting, and jaundice, so treatment is still needed. Hepatitis E is an acute infectious disease caused by the hepatitis E virus, which can cause acute liver injury, usually does not turn into chronic hepatitis, and has a certain degree of self-limitation. However, acute hepatitis E can still cause liver injury, and patients may experience symptoms such as loss of appetite, nausea, vomiting, abdominal distension, pain in the liver area, jaundice, fever, and fatigue, so treatment is still needed. For treatment, patients should be allowed to take bed rest, avoid exertion, eat a light diet, supplement enough energy, and also use vitamin C, glucuronolactone and other drugs for liver protection. Most patients with hepatitis E can recover within 3 months. A few patients can develop into severe hepatitis with a poorer prognosis if they are co-infected with hepatitis B virus. Pregnant women with hepatitis E are prone to progress to liver failure with a mortality rate of 10-40%. If hepatitis E is diagnosed, please follow the doctor’s instructions for treatment.