Generally, a negative T-cell positive TB antibody is considered to be infected with tuberculosis, and such people are immunocompromised, and the antibodies produced form an immune complex with the antigen consuming the TB antibodies in the body, while the remaining antibody level does not reach the positive standard. Generally, if the TB antibody is negative but the T cell is positive, it is mostly considered to be infected by Mycobacterium tuberculosis. Because when the human body is infected by tuberculosis bacilli, some people have low immunity, and the antibodies produced form immune complexes with the antigens to deplete the tuberculosis antibodies in the body, and the tuberculosis antibodies present in the body will gradually decrease, and therefore will show a negative level. The main way of transmission of TB is through droplet transmission, followed by the digestive tract, skin and other ways, but it is relatively rare. Common predisposing factors include low immunity, smoking, alcoholism, and prolonged exposure to poor ventilation. Most patients do not have any obvious clinical symptoms in the early stage of the disease, but as the disease progresses further, patients may develop dry cough, low-grade fever, coughing up sputum, hemoptysis, frequent urination, urinary urgency, and painful urination, depending on the location of the lesion. All in all, it is recommended that TB antibody-negative T-cell-positive patients under the guidance of the doctor to do further tests such as sputum smear, chest CT, etc., to make a clear diagnosis, and cooperate with the doctor for active treatment.