Post-pregnancy uterine separation refers to the presence of a gap in the mucosal layer of the anterior and posterior walls, indicating a small amount of fluid accumulation in the uterine cavity. This may be related to the fact that the embryo has just settled into the uterine cavity and a small amount of mucosal exudate has occurred, which may lead to preterm abortion. If there is no discomfort after a mild separation of the uterine cavity, the woman may observe the situation for a while and pay attention to proper rest and avoid straining. If a woman has lower abdominal pain or a small amount of bleeding, a gynecologic ultrasound and blood tests for chorionic gonadotropin and progesterone levels should be done promptly. If the chorionic gonadotropin level is low and the progesterone level is low, hcg injections or progesterone medication should be given for fetal preservation. It is beneficial to raise the hormone level in the body to help the embryo to continue its implantation and growth and development, otherwise, there may be preterm miscarriage evolving into inevitable miscarriage.