Western drugs for treating uterine fibroids are very limited, and the commonly used ones are leuprolide and goserelin. As uterine fibroids are estrogen-dependent benign tumors, the above two drugs can reduce estrogen levels, so they can achieve the purpose of relieving symptoms, inhibiting the growth of fibroids, and making them gradually smaller, but they can return to their previous size after stopping the drugs. If used for a long period of time, they will produce symptoms of menopausal syndrome, such as hot flashes, irritability, osteoporosis, etc. Since the side effects are relatively large, they should not be commonly used. Clinical use of the above two drugs is mainly to facilitate surgery, control symptoms and correct anemia before surgery, so that the fibroid shrinks to reduce the difficulty of surgery. Treatment of uterine fibroids can also use mifepristone as a preoperative drug, because it can antagonize progesterone, the endometrium will thus be stimulated by estrogen for a long time, with the risk of endometrial hyperplasia, so it can not be used for a long time.