The level of pain associated with the removal of sublingual cysts varies as each person has a different body type and tolerance. Sublingual cysts can usually be performed under local anesthesia; therefore, the pain level of the surgery is usually low. However, if the surgery is more complicated and the patient’s tolerance is lower, general anesthesia is used for the procedure. The sublingual gland is located below the mucosa of the floor of the mouth, above the tongue and flanked by the alveolar bone, which makes the surgical area smaller and the field of vision insufficient, making surgery difficult. If the cyst is a relatively large local irritation, which can lead to obstruction of blood circulation or compression of local nerves, it is necessary to separate the submandibular gland duct and lingual nerve of the sublingual gland, and then remove the sublingual gland together with the cyst. Under adequate anesthesia, the patient is usually in no significant pain. Patients with sublingual gland cysts should seek prompt medical attention and choose the appropriate treatment according to their condition and personal tolerance level in order to minimize pain.