There are more causes of swollen, hard and itchy bumps on the hands, including urticaria, papular urticaria and scabies. 1. Urticaria: limited edema of the skin and mucous membranes due to a temporary increase in vascular permeability. Patients are often suddenly self-conscious of itching skin, soon appeared in the itchy parts of the size of the red masses, round, oval or irregular, can be isolated distribution or expansion of the fusion into a piece, the skin surface is uneven. 2. papular urticaria: mostly caused by mosquito bites, at the beginning of the micro-red papules, followed by mung beans or peanuts the size of the red doughnut-like damage, some for the harder corn grain pimples, scratching was doughnut-like edema, often accompanied by intense itching. 3. Scabies: mainly caused by the human scabies mite. Lesions are mostly symmetrical, located in the tender parts, manifested as papules, papules and tunnels, papules about the size of a grain of rice, light red or normal skin color, accompanied by intense itching. There may be other reasons for the appearance of swollen, hard and itchy bags on the hands, please consult a doctor in a timely manner, after clarifying the cause of the standardized treatment.