Creatinine clearance and glomerular filtration rate are not the same, but creatinine clearance is usually used to roughly assess glomerular filtration rate in clinical practice.
Glomerular filtration rate refers to the amount of ultrafiltrate produced by both kidneys per unit of time (generally referred to as per minute), and is an important indicator of renal function. In general, the glomerular filtration rate in normal adults is about 80-120ml/ (min-1.73m²).
The glomerular filtration rate cannot be measured directly, and the clearance rate of creatinine, a waste product of human metabolism, is often used to reflect the glomerular filtration rate. Because the amount of creatinine produced each day is relatively constant and can all be filtered through the glomerulus, the tubules basically do not reabsorb and secrete very little, so the glomerular filtration rate response is relatively accurate.
Glomerular filtration rate is an important indicator for evaluating renal function. Patients with abnormal glomerular filtration rate should go to the hospital in time for treatment under the guidance of professional physicians.