How to remove skin pigmentation depends on the specific cause of the disease, the more common ones are chloasma, freckles, age spots, etc. The common treatments are medication and laser treatment. 1. Melasma: Melasma is a skin pigmentation spot on the face, which is related to the hormone level in the body, and it should avoid taking drugs that cause hormone level changes. The main treatment method is to apply hydroquinone cream, azelaic acid, retinoic acid and fructic acid for chemical exfoliation, and it can also be treated by laser and intense pulsed light. 2. Freckles: Freckles are brown dotted pigmentation spots, which can be treated with medicines, mainly hydroquinone cream, retinoic acid cream and vitamin E cream, and can also be treated by laser. 3. Age spots: age spots are related to skin aging genetic susceptibility and other factors, most of them do not need treatment and will not affect the body, but if you pay attention to the image, you can undergo laser treatment, including Q-switched laser, Intense Pulsed Light, Carbon Dioxide Laser and so on. Skin pigmentation is recommended to choose the appropriate treatment method according to the specific cause of the disease, and if you need to use medication, you should strictly follow the doctor’s instructions, and you can’t just use medication randomly.