What is Botox? Botulinum toxin, known as botulinum toxin, is a type A toxin secreted by the bacterium Clostridium botulinum during the reproduction process. It was originally a drug for the treatment of muscle nerve hyperfunction because of its disruptive effect on excitatory nerve mediators. It is mainly used clinically to treat muscle spasms, corns, cerebral palsy, strabismus, etc. How can Botox be used for cosmetic purposes again? In 1986, a Canadian ophthalmologist accidentally discovered that this drug, which is used to paralyze muscle nerves, could make the wrinkles under the patient’s eyes disappear. So she told her husband, who is a professor of dermatology, about the surprise. Later, the couple collaborated on research and eventually introduced Botulinum Toxin Type A to the field of skin wrinkle reduction, which was first reported in 1990 and sparked the so-called “BoTox Revolution” in the history of cosmetology. How does botulinum toxin reduce wrinkles? It is because it inhibits the release of acetylcholine from the presynaptic membrane of peripheral motor nerve endings, blocking the transmission of information between nerves and muscles, thus causing relaxation paralysis of muscles. To put it more directly, Botox eliminates wrinkles by paralyzing the muscles so that they do not have the ability to beat. What are the features of Botox for wrinkle reduction? It has the characteristics of small damage, non-invasive, quick effect, easy to operate, and does not affect work. Compared to traditional methods such as chemical peels, facelifts, collagen injections, fat recharging or small incisions to remove wrinkles, it only requires a dose of Botox to be injected into the forehead or between the eyebrows, and the whole process takes only a few minutes and is painless. Its benefits are undeniable. How effective and limited is Botox for wrinkle reduction? A single injection of Botox directly into the wrinkles will gradually smooth out the wrinkles in 3 to 14 days. And the maintenance effect of wrinkle reduction is usually between 3 months to 6 months. For long-term effectiveness, 3 to 4 injections per year are required. It is known that general crow’s feet, forehead lines, frown lines, nose lines and neck wrinkles can be removed by using Botox for wrinkle removal. Who can’t use it? Pregnant women, nursing mothers, patients with myasthenia gravis, allergic patients, people with ptosis and patients with internal diseases such as heart, liver, lung and kidney cannot use Botox for wrinkle removal. Is Botox toxic? Yes. Botox has always been prescribed as a highly toxic drug and can be lethal in certain doses. Of course, it is safe in very small doses when used for wrinkle reduction, but its toxicity and side effects are, after all, objective. As long as it is done safely, it will bring joy to people. What is the toxic lethal dose of Botox? 2500 units. Each vial is 100 units. Think of a doctor who would not give 25 vials of Botox to a client!