Soreness of the stomach at 15 weeks of pregnancy may be caused by physiological phenomena, pre-miscarriage and other reasons. 1. Physiological phenomenon: after pregnancy with the increase of gestational weeks and uterine enlargement, 15 weeks pregnant uterus bottom has reached the umbilicus between the shame, will have a certain pressure on the pelvic floor tissue, and the uterine ligaments have a certain pulling effect, so that the stomach has a feeling of soreness, accompanied by a slight abdominal pain, this is a normal physiological phenomenon, do not need special treatment. 2. Pre-eclampsia: It causes pain in the lower abdomen, which makes the stomach feel sore and swollen, and may be accompanied by a small amount of vaginal bleeding, ultrasound examination may suggest normal fetal development, combined with the history and clinical manifestations can assist in the diagnosis. It is necessary to follow the doctor’s advice to rest appropriately, and actively preserving the fetus treatment. When the stomach is sore and swollen in the 15th week of pregnancy, it is necessary to go to the hospital, under the guidance of the doctor to clarify the specific causes of the disease, and actively deal with it.