Patients with hepatitis B who have significant liver damage may experience gastrointestinal discomfort. In addition to symptoms of pain or discomfort in the stomach, there may also be discomfort in the lower abdomen, usually referred to as stomach pain. The stomach pain may be accompanied by abdominal distension and may also be gastrointestinal pain. In patients with hepatitis B who have significant cirrhosis and often experience indigestion, the stomach pain may be related to hepatitis B disease. Even if hepatitis B disease is the cause, stomach pain is not a direct result of hepatitis B. It is usually a discomfort of the gastrointestinal tract, which can be treated by applying relevant means. If the stomach pain is not relieved after treatment, intestinal problems can also be ruled out. It is still necessary to consider liver diseases, which may be caused by conditions such as liver cancer. The pain will be concentrated in the right upper abdomen or the hypochondrium, and there may also be pain when pressure is applied.