Touching lymph nodes for a long time may cause lymph node hyperplasia and cause lymphadenitis. Lymph node hyperplasia is usually considered benign, while malignant lymph node lesions are usually lymphoma and metastatic lymph node cancer, mostly caused by metastasis of stomach, lung and thyroid cancer. Lymphoma is mostly caused by genetic mutation. For benign lymph node hyperplasia, if there are no clinical symptoms, it can be considered for observation without special treatment. Acute lymphadenitis caused by frequent touching of lymph nodes with hands is mostly caused by bacterial invasion, and common bacteria include Staphylococcus aureus and Streptococcus hemolyticus. First of all, sensitive antibacterial drugs should be selected for treatment, commonly used are first-generation cephalosporins, penicillin, macrolides, such as roxithromycin, cephalexin, amoxicillin clavulanic acid potassium, etc. Severe patients also need intravenous infusion treatment. If the redness and swelling are more obvious, you can also consider giving magnesium sulfate wet compresses to reduce the redness and painful symptoms. When an abscess is formed, it needs to be given promptly with incision and drainage, cleaned with hydrogen peroxide, and drainage strips placed.