Nifurtimox vaginal tablets start to melt after about 15-20 minutes of insertion into the vagina. In case of acute inflammation of the vagina, sometimes when inserting nifurtimox, local irritation may occur, such as burning sensation or local pain, but if it is not serious, these symptoms will disappear naturally. If local itching is serious after the drug is administered, it is likely to be caused by allergy to the drug, and it is recommended to stop using it and switch to other drugs for treatment. In addition, you should not have sexual intercourse or eat spicy and acidic food during the medication period, as this may aggravate the local inflammatory symptoms of the vagina. In clinical practice, it is also recommended to use nifurtimox vaginal tablets only under the guidance of a doctor.