The anti-tuberculosis quadruple drug is a free treatment provided by the CDC. The quadruple drug consists of four anti-tuberculosis drug components: rifampin, isoniazid, pyrazinamide, and ethambutol. All four drugs have their own side effects, but overall liver function impairment is most common, mainly in the form of elevated glutamate transaminase, glutamic oxalacetic transaminase, and glutamyl transpeptidase. In addition, all drugs have the potential to cause allergic reactions such as rashes, and other drugs have their own specific adverse reactions. For example, ethambutol may have adverse reactions to the optic nerve, so it is important to visit a hospital with vision problems and to discontinue the drug as soon as an adverse reaction to the optic nerve is detected. Pyrazinamide may lead to elevated uric acid and cause manifestations such as joint pain, and isoniazid may cause manifestations such as peripheral neuritis.