There are many causes of stiffness, flexion and extension pain in the middle finger in the morning, such as rheumatoid arthritis, osteoarthritis, tenosynovitis and strain injury, etc. Different causes of different medications need to be used, the more common are non-steroidal anti-inflammatory drugs, glucocorticoid drugs and so on. 1. Rheumatoid arthritis: it is an autoimmune disease, with the typical manifestation of morning stiffness, mostly relieved after activities. It can be treated with non-steroidal anti-inflammatory drugs such as diclofenac sodium, glucocorticoid drugs such as prednisone, and anti-rheumatic drugs such as methotrexate. 2. Osteoarthritis: mostly seen in the degenerative changes of the finger joints, the clinical mainly give ibuprofen and other non-steroidal anti-inflammatory drugs, if necessary, can also be injected into the joint cavity of the glucocorticoid drugs such as hydroprednisone treatment. 3. Tenosynovitis: aseptic inflammation caused by trauma and strain injury of the middle finger, non-steroidal anti-inflammatory drugs such as diclofenac sodium can be given to relieve pain, and when the effect is not good, local closed injections can also be carried out, such as local anesthetic drugs such as lidocaine and other glucocorticoid drugs such as triamcinolone acetonide, and so on. 4. Strain: mostly due to the strain of the middle finger, weight bearing and other reasons, the tendon of the middle finger when the pain is obvious need to brake and rest, and can use non-steroidal anti-inflammatory drugs, such as Loxoprofen sodium and so on. It is recommended that the patient go to the hospital, improve the auxiliary examination, in order to clarify the condition, the drugs need to be used under the guidance of a professional physician.