Kidney deficiency refers to the deficiency of essence and yin and yang of the kidney, which differs from kidney yang deficiency, kidney yin deficiency, kidney qi deficiency and kidney essence deficiency. The drugs for treating kidney deficiency also have different herbal and proprietary medicines with these types, such as Right Return Pill, Jin Kui Kidney Qi Pill, Liu Wei Di Huang Pill, Zhi Bai Di Huang Pill, Zuo Gui Pill and other types of drugs. The clinical use should be applied according to the clinical evidence, for example, kidney yang deficiency can use Right Return Pill and Jin Kui Kidney Qi Pill, kidney yin deficiency can use Liu Wei Di Huang Pill and Zhi Bai Di Huang Pill. The application of these drugs must be based on the constitution and reality. If there is dampness-heat or cold-dampness, it is recommended to consult a doctor at the hospital before deciding on further use. Nowadays, there are many drugs for kidney supplementation on the market, and there are more types of preparations. We should not only pay attention to the indications but also the contraindications, which may be more important, such as patients with fire, damp-heat constitution, cold-damp constitution or comrades who need to be conditioned, and need to be further applied under the guidance of a doctor is more reasonable.