Oesophageal inaccessibility may be a temporary obstruction caused by edema, ulcer, tumor, or pancreatic achalasia, etc. It should be treated for the cause. Edema and ulcer-related obstruction should be treated with decongestion, acid suppression, prokinetics, and mucosal protection; tumor should be treated surgically; and cardia dystrophy should be treated with transoral endoscopic sphincterotomy. 1. Temporary obstruction: edema, ulceration leads to congestion and edema of esophageal mucosa, causing temporary obstruction of esophagus, which can be improved by decongestion, acid suppression, promotion of power and protection of mucosa, such as heptadecyl saponin sodium, omeprazole, domperidone, and magnesium alumina carbonate chewable tablets. 2.Tumor:esophageal submucosal masses, polyps, malignant tumors lead to esophageal obstruction, which should be treated endoscopically by resection of the lesion, and surgical operation if necessary. 3. cardia dystrophy: the muscle relaxation disorder of esophageal cardia, causing the lower end of the esophagus to open poorly, stenosis, blockage, can be carried out through the mouth endoscopic esophageal sphincterotomy. The esophagus should be immediately to the hospital to identify the cause of the esophageal obstruction, under the guidance of the doctor treatment.