Fasting blood glucose of 13 mmol/L and 2-hour postprandial blood glucose of 18 mmol/L require treatment. Fasting blood glucose 13mmol/L, 2 hours postprandial blood glucose 18mmol/L belongs to a relatively high level, if the first diagnosis of diabetes mellitus patients need to be hospitalized insulin intensive treatment to reduce glucotoxicity on the islet function of the damage, including the “three short and one long” insulin such as 3 shots of meningococcal insulin plus 1 shot of insulin with glycerin, 3 shots of premixed insulin, insulin pump therapy. insulin, and insulin pump therapy. If patients with non-primary diagnosis of diabetes mellitus, fasting blood glucose 13mmol/L, 2 hours after meal blood glucose 18mmol/L indicates that the blood glucose control is very poor, the current glucose lowering program is not good, can be adjusted after the intensive treatment of insulin glucose lowering program, adjusting the dose of glucose-lowering drugs or add a glucose-lowering drug, combined with diet, exercise therapy. Fasting blood glucose 13mmol / L, 2 hours after meal blood glucose 18mmol / L should go to the hospital, under the guidance of the doctor’s treatment. The use of hypoglycemic drugs must follow the doctor’s instructions, not blindly use their own drugs, in order to avoid serious consequences.