If a large amount of alcohol is consumed 1 day before the physical examination, it may lead to acute damage to liver function, because about 5% of alcohol is metabolized in the lungs, about 5% in the kidneys, and about 90% in the liver, and ethanol is metabolized by ethanol dehydrogenase to acetaldehyde and acetaldehyde dehydrogenase to acetic acid, and the whole process will lead to liver damage. If a large amount of alcohol is consumed, it will lead to a significant increase in glutaminase and glutamic oxalacetic aminotransferase, and may also lead to a significant increase in total bilirubin, direct bilirubin, and indirect bilirubin.