The severity of a pinprick on a nerve depends on what nerve is being pierced. Nerves are widely present in the human body, and peripheral nerve endings can exist under the skin in various parts of the body, and there are usually nerves accompanying the blood vessels. Therefore, when performing intramuscular injections or intravenous injections, it is very likely that the nerves around the puncture site will be injured, but generally this injury to the nerves will not cause any significant dysfunction, but usually only some pain. However, when injecting the gluteus maximus muscle, it is important to choose the correct positioning point and positioning method, otherwise the sciatic nerve will be easily injured. The sciatic nerve is a very important innervation nerve in the lower body, and once damaged, it is likely to cause pain, numbness and other symptoms in the limbs, and even affect movement.