There is no relation between delayed menstruation and taking folic acid, which is a vitamin that is generally recommended for proper folic acid supplementation if the patient is in a state of pregnancy preparation. Supplementation during the first trimester to the first trimester of pregnancy can effectively prevent malformations in fetal nervous system development. Also, folic acid has a good therapeutic and preventive effect on patients with megaloblastic anemia, or homocysteinemia, and folic acid often does not affect the patient’s endocrine regulation. The main reasons for delayed menstruation are as follows: First, the patient’s own living habits and dietary habits lead to endocrine disorders, causing delayed menstruation. Second, the patient’s recent mental state of excessive tension, anxiety or staying up late, insomnia, lack of sleep, resulting in delayed menstruation. Thirdly, recent cold or eating cold and cold food can also lead to delayed menstruation. In daily life, as long as nutrition is balanced and work is combined with rest, the symptoms of delayed menstruation will not occur.