Skin cuticle hardening may be caused by chronic eczema, tinea versicolor and other causes. 1. Chronic eczema: chronic eczema may be related to chronic infection lesions, endocrine and metabolic changes, blood circulation disorders, immune system function abnormalities and other factors, mainly manifested as local skin roughness and hypertrophy, the phenomenon of hardening of the stratum corneum, accompanied by intense itching symptoms. 2. Tinea versicolor: hand due to fungal infection can appear after erythema, papules, blisters, etc., scaly tinea versicolor manifested as excessive keratinization of the hands, a large number of scales, skin roughness. The hardening of the skin stratum corneum may also have other causes, it is recommended to go to the hospital in time to improve the examination and give targeted treatment after the cause is clear.