Callus hard and feel pain can be relieved by physical therapy, medication, surgery and other ways, should be under the guidance of the doctor to choose the appropriate treatment. 1. Physical therapy: callus, commonly known as callus, with obvious pain symptoms, can be treated by physical therapy means such as liquid nitrogen freezing, carbon dioxide laser and other treatments. In addition, you can also use hot water to soften the callus and then use a scalpel to remove the surface of the stratum corneum, to avoid friction caused by pain. 2. Medication: The most commonly used medication for callus is salicylic acid plaster, which can be applied after removing the cuticle on the surface of callus to relieve the pain. 3. Surgery: If the callus is caused by local deformity, it can be treated by surgical treatment of deformity to eliminate the factors that lead to the friction of the callus and remove part of the stratum corneum appropriately. In this case, you should go to the hospital in time, under the guidance of the doctor for symptomatic treatment, avoid unauthorized medication or treatment.