Polycystic ovary syndrome diagnostic criteria The three unique features of polycystic ovary syndrome are polycystic ovaries, hyperandrogenemia and anovulation, but the heterogeneity of the disease means that not all patients will have all three of these abnormalities. Diagnostic criteria for polycystic ovary syndrome: Meets both of the following criteria: Hyperandrogenemia Ovarian ovulatory dysfunction Meets any two of the following three criteria: Hyperandrogenemia Ovarian ovulatory dysfunction Polycystic ovaries Meets both of the following criteria: Hyperandrogenemia Ovarian dysfunction or polycystic ovaries or both