Major triple yang mainly refers to positive hepatitis B surface antigen, hepatitis B e antigen and hepatitis B core antibody. There are two main clinical types of major triple yang: 1. Chronic hepatitis B virus carriers, when patients may be in the immune tolerance period and have no obvious clinical symptoms. The patient’s clinical symptoms are not obvious. 2. The active stage of chronic hepatitis B, when glutathione and hepatitis B virus DNA quantification will be significantly elevated, the patient may also appear more obvious clinical manifestations, need to give timely antiviral and liver protection treatment.