Sleeping in the middle of the night dry mouth and throat is mostly due to physiological reasons, such as indoor temperature is too high, dinner eaten too salty; also see the pathological reasons, certain diseases such as colds, diabetes and so on. 1. Physiological reasons: such as high indoor temperature, or open breathing, dinner is too salty, too full, sleep in the middle of the night will appear dry mouth, dry throat, before going to bed you can drink water, to avoid eating too salty dinner. 2. Pathological causes: ① certain diseases, such as colds, nasal congestion, nasal ventilation is blocked, breathing through the mouth, there is a dry mouth, there will be a sore throat, etc., to drink more water, eat more fresh fruits and vegetables. ② diabetes, blood sugar control is not stable, sleep in the middle of the night, can appear dry mouth, dry throat. You can drink more water and take hypoglycemic drugs, such as metformin, under the guidance of your physician. After excluding physiological reasons, you need to go to the hospital in time, under the guidance of the doctor for reasonable treatment.