Urine protein negative does not mean that kidney disease will not continue to progress, urine protein negative kidney disease may still progress, so you need to follow the doctor’s advice to continue treatment, usually pay attention to lifestyle, diet and nutritional balance, to avoid recurrence of kidney disease. Urine protein is a protein normally produced by the human body, there will be a small amount of excreted through the urine, the normal value of urine protein is less than 0.1g/L. When kidney function injury, glomerular capillary wall damage, resulting in a large number of proteins filtration and absorption is reduced, resulting in proteinuria. The concentration of proteinuria can reflect the severity of kidney injury. Generally after treatment, the urine protein will drop to normal value, which means that the kidney function is basically back to normal, but it does not mean that the kidney disease will not recur or continue to progress. Because there are many causes of kidney disease, such as immune or drug-induced kidney disease, if autoantibodies continue to produce, or continue to use drugs with nephrotoxicity, may lead to the progression or recurrence of kidney disease. Even if the urine protein turns negative, the kidney disease may still recur or progress, so it is recommended that kidney disease patients should standardize the treatment under the guidance of physicians.