Terbinafine and ketoconazole are both antifungal drugs with the same indications, so they generally do not need to be used at the same time, and should be standardized under the guidance of a doctor. Terbinafine and ketoconazole are both antifungal drugs, generally used in the treatment of ringworm, tinea corporis, lichen planus, tinea pedis, and skin candidiasis, etc., with antibacterial and antiseptic effects. Under normal circumstances, terbinafine and ketoconazole do not need to be used together, in a period of time to use a separate drug can be, need to follow the doctor’s instructions for medication. Avoid combining drugs, causing drug-drug interactions. Adverse reactions such as skin flaking, itching, and burning sensation may occur after terbinafine use; tingling and itching may occur after ketoconazole use. It is contraindicated for breastfeeding women and those who are allergic to terbinafine; it is contraindicated for those who are allergic to ketoconazole, sulfites, and imidazoles. If you want to use topical terbinafine or ketoconazole, it is recommended to go to a regular hospital to consult a doctor and use the medication under the doctor’s guidance, and not unauthorized use of drugs.