Taking a statin to begin to lower fat fast and the rapid action of the drug is related to the drug, but the drug’s lipid-lowering effect is limited, and eventually there will be a decline in lipid-lowering effect. The main effect of statin drugs is to limit the cholesterol synthesizing enzyme, for patients with hyperlipidemia, after oral statin drugs, there will be a short-term reduction of cholesterol significantly, and quickly play a role in lowering cholesterol. The cholesterol-lowering effect of statin is limited, which may be related to the degree of enzyme restriction of statin drugs, which cannot restrict the cholesterol synthesizing enzyme without any limitation. After the cholesterol has been lowered to a certain level, the effect of statin will be weakened, if you need to continue lipid-lowering treatment, you need to combine with other drugs, such as cholesterol absorption inhibitor ezetimibe. The process of taking statin should pay attention to strengthen the cholesterol monitoring, to understand the effect of lipid-lowering, and the adverse effects of statin drugs include abdominal discomfort, nausea, vomiting, transaminase elevation, etc., allergic to the drug components, severe hepatic function impairment and other patients are prohibited. If necessary, under the guidance of the physician to use a combination of lipid-lowering treatment. The specific use of drugs need to follow the doctor’s instructions.