Side effects of Trimethoprim include hyperpigmentation, hirsutism, and skin atrophy. Trimethoprim is suitable for contact dermatitis, eczema, neurodermatitis, tinea cruris, tinea pedis, etc. It has anti-inflammatory, anti-itching, anti-allergic as well as antibacterial effects. Adverse reactions such as itching and burning sensation of the skin may occur after the use of the drug, which should not be used for a long time and over a large area, and contact with the mouth, nose, eyes and other parts of the body should be avoided when using the drug. After 4 weeks of use, the symptoms are not relieved, you need to go to the hospital, if you suffer from heart disease, hypertension or hepatic insufficiency, it should be used with caution, and it is prohibited for those who are allergic to this product. If you need to use Trimethoprim, it is recommended to go to a regular hospital to consult a doctor and use the medicine under the doctor’s guidance.