Syphilis (syphilis) is caused by the syphilis spirochete and is transmitted by contact. Clinically, it can be divided into 3 stages: initial, second stage, and third stage (late stage). Syphilis of stomach is a rare gastric disease caused by syphilis spirochetes invading the stomach lining. The majority of patients with syphilis of the stomach are male, and most of them are 30-50 years old. It is a rare disease of the stomach. In the early stage of syphilis, there is no significant change in gastric acid, and in the late stage, there is a decrease in gastric acid secretion. In advanced syphilis, there is narrowing of the gastric sinus, weakened peristalsis of the gastric wall and the formation of large irregular ulcers after rupture of the dendritic swelling, which are difficult to distinguish from cancerous ulcers in appearance. Prevention: 1. Within 3 months, any sexual partner who has been in contact with infectious syphilis should be examined, diagnosed and treated. 2, early syphilis in the treatment period to prohibit sexual intercourse.