The increased permeability of gastrointestinal mucosa is mostly seen in gastric cancer and colon cancer due to necrosis and shedding of cancerous tissues, resulting in increased permeability of the corresponding gastrointestinal mucosa and loss of plasma proteins by leakage from the gastrointestinal tract. Gastric cancer is also a common cancer in our life, and the mortality rate is relatively high, and gastric cancer is caused by improper diet or viral infection, for example, some people like to eat raw food, which has more bacteria and viruses, or those who have irregular diet and often skip breakfast have a higher chance of getting sick, so we should understand the cause and treat it early. What are the early symptoms diagnosis? 1.Abdominal pain, warmth and loss of appetite: this symptom is long term, basically, if you have stomach cancer, you will have this symptom every day, unlike ordinary stomach disease, although stomach disease will also have this symptom, but not so much that you will feel abdominal pain and warmth every day, as long as the condition has recovered a little, these symptoms will disappear, while stomach cancer will not stop and will continue to be painful. 2.Upper abdominal discomfort: this is also a more obvious symptom, and many people will ignore such a symptom in the early stage, thinking it is just an ordinary stomach disease. At the beginning, it is only a slight pain, and there is no regularity, and after eating, it will feel more painful and need to take medicine to relieve it, and as the condition worsens, the pain will become more and more powerful, and the frequency will become faster and faster. 3.Lack of appetite and indigestion: Since stomach cancer will lead to indigestion and poor appetite, the whole person will lose weight faster, and if the stomach has problems, no matter what nutritious things you eat, you can’t absorb them, so the whole person will lose weight especially fast, so if you have such symptoms, you must pay attention to it. Therefore, if you have such symptoms, you must pay attention to them. If you have long time stomach pain, heavy stomach warmth, frequent nausea and can’t eat anything, you should go to hospital for a detailed examination, because early stage stomach cancer can be saved, but late stage is very dangerous.