The severity of low fibrinogen should be considered in the context of the primary cause of hypofibrinogenemia. Fibrinogen is a little bit low, if it is caused by liver insufficiency, coagulation disorders, bleeding and consumption and other reasons, then it is more serious, otherwise it is not serious. 1. Liver insufficiency: fibrinogen is synthesized and secreted by liver, if the patient’s liver cell injury, the function of synthesis and secretion of fibrinogen will be decreased, which can lead to low fibrinogen. 2. Trauma, bleeding disorders: if the patient has trauma, bleeding disorders, etc., when the fibrinogen decreases, it is considered that the bleeding leads to excessive consumption of fibrinogen, and the severity of the trauma or bleeding needs to be examined in the first place in this case. 3. Coagulation dysfunction: if the patient has coagulation disorder, especially hypercoagulable state, high risk of thrombosis, the body thrombus formation at the same time fibrinogen activation, carry out its fibrinolytic function, then hyperfibrinolysis can make the body fibrinogen consumption leads to low fibrinogen, and check D-dimer is usually very high, this is more serious, there is a risk of thrombosis. 4. Unknown cause: If the patient has low fibrinogen, but the examination of liver function is normal, normal coagulation function, no bleeding disorder, regular monitoring of fibrinogen content can be. Fibrinogen is low, can go to the hospital in time, follow the doctor’s instructions for reasonable treatment.