If a diabetic patient has general weakness and other discomfort, he or she can take oral medication to improve his or her strength, and can take oral coenzyme Q10 or vitamin D. If a diabetic patient has general weakness and other conditions, he or she is also advised to improve the relevant tests to rule out whether the general weakness is caused by long-term blood sugar fluctuations or long-term hypoglycemia. It is recommended that patients monitor their blood glucose several times and wear 24-hour ambulatory blood glucose monitoring to see how their blood glucose is doing. If the blood glucose control is stable and general weakness occurs, oral medication can be taken to improve strength. If the general weakness is caused by blood glucose fluctuation, it is recommended to adjust the glucose-lowering program. It is also necessary to improve thyroid function to rule out the presence of hypothyroidism.