How long it takes for Minoxidil rub to work varies from person to person. The time to take effect varies from person to person. Usually it should take at least 1-2 months for the effect to be seen gradually. Minoxidil rub does not work for everyone. It is usually only effective for male pattern baldness or baldness patients, and only if the patient’s hair follicles are still active. Minoxidil is initially a hypotensive drug that dilates the peripheral blood vessels and has an effect of increasing nutrition to the hair follicles. When Minoxidil is used for a long time, it has the effect of promoting hair growth in some hypertensive patients. Therefore, it was used as a topical minoxidil rub to treat male pattern baldness or baldness at a later stage. The effectiveness varies from person to person and its related to whether the hair follicles survive in baldness patients. Minoxidil must be used for a long time and usually takes several months to be effective. Minoxidil should be used only about 1mL at a time, not more than 2mL. spray minoxidil on the scalp, local massage 3-5min. minoxidil is prohibited for pregnant and lactating women.