There are seven high-risk factors that can cause malformations in fetal heart development: 1. A family history of congenital heart disease. It is not uncommon for siblings to have congenital heart disease at the same time, and for parents and children to have congenital heart disease at the same time, and the nature of the disease is very similar. If the first child born to a mother with congenital heart disease, the likelihood of the second child having the disease is about 2%; if two consecutive children are born with congenital heart disease, the number of new children with congenital heart disease may increase to 10%. If the mother suffers from precocious heart disease, the risk of the second generation suffering from precocious disease is 10%. 2, pregnant women with untreated and uncontrolled diabetes mellitus, the risk of congenital heart disease in the fetus is 2%. 3, pregnant women exposed to teratogenic drugs in early pregnancy, such as lithium, phenytoin sodium or steroids, etc., can lead to a 2% prevalence of fetal congenital heart disease. 4, early pregnancy by radioactive substances such as X-rays, isotopes and other excessive exposure. 5.Viral infection. Women in the first three months of pregnancy, especially the 3 weeks-8 weeks of pregnancy, if infected with viruses, the fetus is prone to cardiovascular malformations. Among them, rubella virus is the main culprit of fetal precocious heart disease. In addition, influenza, mumps, coxsackie virus, herpes virus, etc. are often the “perpetrators” of pediatric precocious heart disease. 6, consanguineous marriage. Consanguineous marriage is a high risk factor for fetal malformation and the occurrence of precocious heart disease. 7, bad habits. Pregnant women are addicted to “swallowing fog” or husband smoking, wife “passive smoking” can make fetal malformations or the occurrence of pediatric precocious heart disease. The incidence of pre-cardiac disease in infants, babies born to smoking mothers is two times that of non-smoking mothers. Conception after drinking” can cause chromosomal abnormalities in the fetus, and most babies born with alcoholism have cardiovascular abnormalities. Early detection of prediabetes is essential for eugenics. At 20-28 weeks of gestation, a fetal heart “defect” can be clearly detected using a cross-sectional ultrasound heart scanner. In addition, the presence of ascites or edema can be detected, which can lead to the detection of cardiac malformations in the fetus.