Acne around the mouth can be caused by acne, perioral dermatitis and other reasons. 1. Acne: mainly related to the increased secretion of sebaceous glands and abnormal levels of androgens, occurs on the cheeks, forehead, mouth, mainly characterized by pimples, papules, pustules, cysts, often accompanied by seborrheic overflow. 2. Perioral dermatitis: Perioral dermatitis is an inflammatory skin disease that occurs around the mouth, the cause of which is still unclear, and may be related to fluoride toothpaste, excessive use of facial cosmetics, etc. It manifests itself in the form of red pimples and pimples around the skin around the mouth, which may be accompanied by mild to moderate itching and burning sensation. Acne around the mouth may also have other causes, it is recommended to go to the hospital in time to clarify the cause of the disease, and follow the doctor’s instructions for treatment.