I. Understanding the etiology and pathogenesis of gastric cancer According to Dr. Sun, although there is no record of “gastric cancer” in Chinese medicine, many of the symptoms and signs of gastric cancer are similar to those of gastric cancer. When we analyze the clinical symptoms of gastric cancer, they are “stomach pain”, “choking and diaphragm”, “subcardiac abnormalities”, “regurgitation”, “stomach regurgitation” and “stomach regurgitation” in Chinese medicine. The symptoms of gastric cancer belong to the categories of “gastric pain”, “choking and diarrhea”, “subcardiac puffiness”, “regurgitation” and “stomach regurgitation”. For example, in the Yellow Emperor’s Classic of Internal Medicine, it was first recorded that “those with stomach problems have abdominal _ distension, stomach and epigastric pain in the heart …… and diaphragm and pharynx are not accessible, and appetite is not maintained” and “eating and drinking are not maintained, diaphragm is not accessible, and evil is in the stomach and epigastric region”. In the Golden Kernel, it is written that “vomiting during the morning meal, vomiting during the evening meal, and vomiting during the evening meal, and failure to dissolve the stored grain is called gastric rebellion”, and it is pointed out that the pathogenesis is “spleen injury without grinding”; in the Treatise on the Origin of Diseases, it is further pointed out that “vomiting during the morning meal, vomiting during the evening meal, vomiting during the evening meal, and vomiting during the evening meal. Zhu Danxi said “regurgitation of the disease …… constipation less, up and down does not pass”, and said “probably because the blood is depleted, the stomach and epigastric also haggard, in the upper near the pharynx, water and drink is feasible, food is difficult to enter, sometimes can eat, into also not much, called choke; its haggard in the lower, and the stomach for the choke. The haggard in the lower, and the stomach is close, although the food can enter, difficult to enter the stomach, a long time to come back out, the name is called diaphragm, also known as turning the stomach”, pointed out that choking diaphragm, turning the stomach of the pathogenesis is “blood depletion, the stomach and cavity haggard”; Ming? Zhang Jinyue said that “food into the opposite out of the Yang deficiency can not be transformed …… food can not be down from the gas knot can not also be line”, “choke diaphragm evidence, must be worried about thinking, accumulated labor and depression, or excessive wine and sex injury Yin, Yin injury is depleted essence and blood, gas can not The “choking diaphragm disease in the upper, essence and blood dried up, then dry knot disease in the lower”, enriched the pathogenesis of choking diaphragm, stomach, and that “juveniles rarely see this evidence, but the middle-aged depletion of the injured have more”; Ming? Zhao Xian can “Medical Guan” also believes that “only men who are old have it, less choking diaphragm”, and in the “Choking Diaphragm” a detailed comparison of choking diaphragm and stomach turning: “choking diaphragm, hunger to get food, but choking and welcome rebellion between the throat and chest and diaphragm, above the stomach, before entering the stomach, that is, with phlegm and saliva out; stomach turning. The stomach is said to be turned over because the food and drink are twice as normal and all enter the stomach, but the food is vomited in the morning and vomited in the evening, or vomited in a couple of hours, or accumulated to a day and a night, the abdomen is distended and unbearable and vomited again, the original material is sour and odorous, this is into the stomach and out, so it is called turned over”, from these symptom descriptions and contemporary clinical manifestations of gastric cancer, choking diaphragm is very similar to cardia cancer, and turned over stomach is similar to gastric body and sinus cancer. In the Qing Dynasty, the “Golden Guide to Medicine” records that “the three yang knots are called diaphragm. Three yang is the stomach, small intestine, large intestine. The three provinces of heat knot does not disperse, burning fluid, the mouth of the stomach for the cardia, small intestine on the mouth for the pylorus, the mouth of the large intestine for the pelvic door, the three provinces of fluid are injured, the three doors naturally dry …… cardia dry, the road into the water and grain is narrow, so food can not go down, for choking also. The pylorus is dry, the road to put out the decay is narrow, so the food into the opposite out, for the stomach also. The two evidence stay for a long time, the large intestine conduction of the road is narrow, so the pranic door should be dry and difficult to move”, further pointed out that the cause of choking, diaphragm, stomach turning leading to constipation. Jing Yue Quan Shu play: “diaphragm, between the chest and diaphragm, stomach, or phlegm, or blood stasis, or food stagnation, food into the stomach, can not be reached and vomiting, and gradually under the food that vomit, for regurgitation is carried out”, further expanding the etiology of the pathogenesis, indicating that the cause of choking diaphragm, regurgitation is not only due to Yang Qi deficiency or Qi stagnation, but with phlegm It is also related to phlegm, blood stasis, and food stagnation. Sun summarizes the relevant discussions of the ancients and his own clinical experience for more than 40 years, and believes that the main factors in the development of gastric cancer are: 1. Deficiency of cold in the spleen and stomach Weakness of the spleen and stomach, lack of innate endowment, or due to external cold, excessive consumption of cold food injury to the stomach, labor and fatigue injury to Yang, resulting in the weakness of Yang Qi in the middle jiao, poor Qi flow, loss of elevation, inability to decompose water and grain, and congestion in the middle jiao, then the stomach and epigastric distension and fullness, belching rancid, and even vomiting in the morning and evening, and eating in the evening. vomiting. Or have a long history of gastric disease, gastric depletion, stomach cold, the stomach can not grind food, food into the return, and regurgitation. Such as Zhang Jinyue said “regurgitation, food can enter, into and out of …… to Yang deficiency can not be turned, can be warm can be tonic”. 2, the diet is not moderate hunger and satiety, indulge in oral pleasure, will damage the spleen and stomach. Or over-eating cold, cold accumulation in the Palace, blood and Qi stagnation, cold pain in the stomach and epigastrium; or wanton eating fat, sweet, spicy, over-drinking strong alcohol, spleen and stomach damage, damp heat, fluid depletion, phlegm, gradually into a mass; or over-eating sticky and difficult to dissolve things, accumulate in the Palace, wet and phlegm, damage to the spleen and stomach, spleen injury and not grinding, stomach injury and not descending, spleen loss of health and clearing, stomach loss and descending conduction, congestion in the center, gradually into a mass, even the epigastric fullness, belching Uh retrograde, swallowing acid retching rot, choking, painful eating, food into the return, it becomes regurgitation. For example, the Ming Dynasty “Jing Yue Quan Shu” said: “(regurgitation) or to cool drink in excess, hurt in the wine wet, or to eat cold, defeating its true Yang, …… to damage the stomach gas and natural”; Yu Jiayan in the “Medical Gate Law” pointed out: “over-drinking rolled wine, the The doctor said: “the wine guest more choke diaphragm, good heat is especially more, to heat injury fluid, the throat tube dry, food can not be deep also”, “good heat, more suffer from diaphragm disease. 3, qi stagnation and depression, emotional disorders, the seven emotions too much or not enough, can lead to internal deficiency, qi stagnation and depression, congestion in the veins, yin and yang dysregulation, the three jiao isolation, the application of chemistry does not work, fluid is not smooth, food can not be down. In the Ming Dynasty, Li Zhongzhi’s “Medical Zong Zhi Yi” also said: “The loss of qi and blood, and because of grief and worry, the spleen and stomach are injured, blood gradually depleted, depressed gas and phlegm …… choke by the formation of. 4, qi stagnation and blood stasis qi and blood disharmony, is due to qi depression, qi deficiency, or cold condensation, or heat knot, resulting in the qi mechanism is not smooth, the veins and ligaments stasis, qi and blood stagnation, accumulation over time, that is, into a mass. The “ancient and modern medical science” in the record: “where the food under the hindrance, feel curved and flexed and down, slightly painful, this must have dead blood, the heart under the jail as large as a cup, the morning food and evening vomiting, the evening food and vomiting …… belly lumps, there must be a form of blood”. Chinese medicine believes that qi stagnation must have blood stasis, blood stasis will not pass through the veins, not pass through the pain. The main formula is based on Huangqi Jianzhong Tang, which is used to strengthen the spleen and stomach, elevate the clearing and lowering the turbidity, remove congestion, eliminate food stasis, create new blood stasis, and clear heat and detoxify the toxin, etc. The formula uses Huangqi, Bai Shao, Prince Ginseng, fried The formula uses Huang Qi, Bai Shao, Prince Ginseng, Fried Atractylodes Macrocephala and Fu Ling to strengthen the spleen and stomach, Sheng Ma Ma Ye, Dai Ochre, Ji Nei Jin and Jiao Zha Nang to elevate the clear and lower the turbidity, grind the grain and remove congestion, eliminate food and accumulation, dispel blood stasis and create new blood, and Vine Root and Tiger Balm to clear heat and detoxify. Then, according to the needs of the disease, add and subtract according to the evidence: if the spleen is deficient in Qi, add Mu Xiang and Sha Ren; if the dampness is obstructed, add Cardamom, Almond, Raw Coix Seed, Qing Han Xia and Hou Pu; if the abdominal fluid is accompanied by swelling, add Pig’s ling, Ze Di Di, Han Fang Zi, Che Qian Zi and Gryllotal; if the Qi is stagnant in blood, add Citron, Buddha’s Hand, Di Long, Peach Root, Water Safflower Seed, Ling Xiao Hua, Angelica, Nine Fragrant Worms, Trigonella, Curcuma, Gunnera, Augusta. If it is necessary to warm the middle of the body to relieve pain and subdue rebellion to stop eruption, add cumin, orange kernel, lychee kernel, ocimum sanctum, galangal, aromatic herb; if it is difficult to swallow, add wei ling xian; if it is deficient in kidney essence, add wolfberry, chasteberry, dry lotus grass, turtle plate, turtle nail, raw and ripe ground, angelica, shou wu, mulberry, cow knee, chicken blood vine; if it is deficient in kidney qi, add codonopsis, mulberry cuttlebone; if it is deficient in kidney with bone metastasis, add bone marrow, bone shredder; if it is hot and poisonous, add codonopsis, mulberry cuttlebone. If the kidney is deficient with bone metastasis, add Boneset and Boneset; if the heat is hot and poisonous, add Cao He Che, Half-branch Lotus, Snake Berry, Golden Buckwheat, Shi Shi Jian Dian, and White Flowered Snake Tongue; if the lymph nodes are metastatic or intestinal adhesions, add Acute Seed; if the kidney is incompetent, add Evening Sericea; if there is bleeding or bleeding tendency, add Panax ginseng, Agaricus blazei, and Bletilla; if it is difficult to sleep at night, add Hopshoe Bark, Nightshade Vine, Fried Sour Jujube, Fried Cypress, and Longan Flesh; if the phlegm-heat disturbs the stomach, nausea In case of vomiting and nausea, add orange peel, bamboo rhizome, clear half-xia, loquat leaf or guahua peel, clear half-xia, caudex, wu huohua, and spineflower; in case of phlegm-heat injury to yin, add sage, scutellaria, and clear half-xia; in case of stomach-heat and yin deficiency, add and reduce the formula with yu mei decoction, using yu zhu, lady’s maidenhair, Zhi mu, cow’s knee, raw gypsum, raw earth, and maitong. According to Dr. Sun, stomach cancer patients should abstain from smoking, alcohol, spicy stimulating and greasy products in their diet. However, as for the claim that tea and mung beans reduce the efficacy of traditional Chinese medicine, Dr. Sun said that this claim is not in line with science and pointed out that medicine should be incorporated into food and all meals are medicine. The knowledge of tea can be traced back to the Western Han Dynasty ancient book “Huainanzi”: “Shennong tasted the taste of a hundred herbs, water and springs of sweet and bitter, so that the people know what to avoid. One day encountered seventy-two poison, get tea and solve the “. Subsequently, the Tang Dynasty “herbal collection” pointed out: “the medicine for each disease, tea for all diseases”, these statements indicate that the ancestors of the Chinese people early in practice recognized that tea has detoxification and a wide range of anti-disease function. A large number of modern studies have proved that tea polyphenols (TP), the main component of the medicinal effect of tea, has a variety of effects such as enhancing body resistance, antioxidant, anti-cancer, anti-tumor, anti-radiation, anti-bacterial, anti-virus, hypoglycemic and hypolipidemic, prevention of cardiovascular and cerebrovascular diseases, anti-aging, etc. PAN et al. studied the molecular mechanism of tea polyphenols inducing apoptosis in human gastric lymphoma U937 cells. They found that TP has mitochondrial pathway targeting and induces DNA cleavage factor DFF-45 degradation. Therefore, tea polyphenols can be a new tumor cell apoptosis inducer. Li Shizhen, a medical scientist in the Ming Dynasty, called mung beans “really a good grain for the world” in the “Compendium of Materia Medica”. Mung beans can be cooked to reduce swelling and gas, clear heat and detoxification, quench summer heat and thirst, harmonize the five organs, calm the spirit, replenish vital energy and nourish the skin; mung bean powder detoxifies all kinds of toxins, treats sores and swellings, and heals burns; mung bean skin detoxifies heat and retreats eye shades; mung bean sprouts can detoxify wine and detoxify. However, although mung beans are good, because it is cold, so people with a weak spleen and stomach should not eat more; moreover, mung beans should not be overcooked, so as not to make organic acids and vitamins are destroyed, reducing the effectiveness of heat detoxification. In conclusion, Dr. Sun believes that patients do not need to abstain from eating too much, especially from hearsay, causing unnecessary mental burden to themselves. Patient Gao Moumou, male, 66 years old, from Beijing. He came to our outpatient clinic in May 2001 mainly because of “epigastric pain for more than 5 months and progressive weight loss of more than 10 pounds”. The patient complained of epigastric pain, which was persistent and vague, aggravated after eating, but still tolerable, accompanied by nausea, erratic, acid reflux, loss of appetite, shortness of breath, and weakness, on examination: T 37.2℃, P 82 times/min, Bp 110/70mmHg. No mobile turbid sounds, no edema in both lower limbs. The tongue is fat and light, with thin white coating and weak pulse. Auxiliary examination: Blood count: WBC 6.4×109/L, N 75%, L 20%, Hb 86g/L. Stool occult blood test (+). Gastroscopy showed a 2 cm×2.5 cm deep ulcer with a small amount of blood leakage, hard margins and a cloudy moss on the surface, which was suspected to be gastric cancer, but no microscopic pathological examination was performed. The tumor was 2.0cm×2.3cm in size, with ulcer formation on the surface and 2/10 lymph node metastasis, and was not treated with chemotherapy after surgery because of the patient’s history of old heart attack. The treatment is to strengthen the spleen and stomach, benefit qi and nourish blood, promote clearing and lowering turbidity, eliminate food and stagnation, and supplement with anti-cancer. The first dose was taken every 2 days in 2 doses. Gastroscopy: mucosal congestion and edema on the lesser curved side of the anastomosis, no ulcer was seen. Pathology: moderate chronic inflammation of gastric mucosal tissue. The patient had no conscious symptoms, good appetite, 10 Kg weight gain, and has survived 7 years of healthy follow-up.