Colon cancer is a common malignant tumor in the gastrointestinal tract, with the highest incidence in the age group of 41-50 years old. Early symptoms are not obvious and can be easily ignored, thus delaying treatment and affecting patients’ survival rate. The survival time of patients is related to the early detection of lesions, early detection and early surgical resection can greatly improve the survival rate of patients, and the average survival time of untreated advanced colon cancer patients is only about six months, but there is no treatment plan for advanced colon cancer, but individualized treatment plan must be selected with patient’s specific conditions, such as radiotherapy, chemotherapy, targeted therapy, Chinese medicine treatment, fistula and other palliative treatments. After regular and active treatment, the average survival time of patients with advanced colon cancer can reach about two years, thus achieving the effect of improving patients’ survival time. The survival rate of advanced colon cancer is also related to the patient’s personal constitution and age, disease stage, treatment method, mental state, nutritional status, etc. Through active and effective treatment, the five-year survival rate of advanced colon cancer patients is on the rise. It is recommended that colon cancer patients should seek medical consultation and treatment as early as possible, and also maintain an optimistic mood, good rest and improve their resistance so as to prolong their survival time.