1, in maternity, what is “advanced age” age over 35 years old, that is, advanced age. 2, what are the special features of advanced age, in addition to older age, there are ovarian function, fertility decline, 35-year-old women’s fertility is only 25 years old 50%, to 40 years old, down to 35 years old 50%, so it is easy to get pregnant, easy to abortion phenomenon. In addition, the genetic mutation of advanced maternal age may, chromosomal abnormality probability is elevated, combined with a variety of medical and surgical diseases, increasing the risk of embryonic malformation and pregnancy complications. 3, what should be noted before pregnancy should pay attention to the following before pregnancy: ① genetic counseling, not you ever had a healthy child do not need, as long as the age of women older than 35 years old want to give birth again, the probability of genetic mutation will increase, so all need to carry out genetic counseling; ② pre-pregnancy check, in addition to routine checks, but also need to pay special attention to the function of important organs, including heart function, liver and kidney function, blood pressure and glucose; ② pre-pregnancy check, in addition to routine checks, also need to pay special attention to the function of important organs, including heart function, liver and kidney function ② pre-pregnancy examination, in addition to the routine examination, also need to pay special attention to the function of important organs, including heart function, liver and kidney function, blood pressure and blood sugar, etc.; ③ exercise, help to improve physical quality, improve the quality of eggs, do not trust the so-called health care products or ovarian maintenance treatment, etc.; ④ to avoid bad habits, such as smoking, alcohol, staying up all night. 4, the need for prenatal diagnosis The probability of pregnant women of advanced age giving birth to children with genetic mutations and chromosomal abnormalities is higher than that of young women, so prenatal diagnosis is very necessary, not referring to simple Down’s syndrome screening, but non-invasive DNA or amniocentesis.