The difference between ulceration and ulceration mainly lies in the different degree of damage between the two, ulceration means that the damage is limited to the mucous membrane layer or submucosal layer, while the ulcer damage involves the submucous membrane layer, the intrinsic muscle layer, and even reaches the plasma membrane layer. The appearance of ulceration or ulcerative lesions are mostly seen in the gastric mucosal tissue. Gastric mucosa tissue structure from top to bottom is divided into four layers, respectively, the mucous membrane layer, submucosa, lamina propria and plasma membrane layer. Gastric mucosal ulceration, the lesion is generally limited to the mucosal layer, the serious cases can reach the submucosal layer, but does not involve the intrinsic muscular layer, for superficial lesions. In the treatment, need to comply with medical advice with acid-producing drugs (such as omeprazole, pantoprazole, etc.) and eradication of Helicobacter pylori (such as amoxicillin, metronidazole and other drugs), remove the causative factors, gastric protection treatment for 2 to 3 weeks, most of the mucosal ulcerative lesions can be restored. Gastric ulcer lesions deeper eradication of Helicobacter pylori treatment 2 to 3 weeks later, the need to continue to use acid production gastric protection drug treatment for 6 to 8 weeks before the ulcer surface can be gradually healed, and later need to gastroscopy to review the ulcer healing.