Cough infusion mouth bitter may be related to the infusion of anti-inflammatory drugs (such as clindamycin injection), violent coughing led to bile reflux and so on. 1. anti-inflammatory drugs: cough infusion mouth bitter may be related to the infusion of anti-inflammatory drugs, such as clindamycin injection, etc., in the process of infusion, there will be gastrointestinal reactions, manifested in the mouth bitter and other adverse reactions, when the infusion stops, the mouth bitter symptoms will disappear. Some drugs can also damage the mucous membrane of the digestive tract, which in turn affects the secretion of digestive juices in the mucous membrane of the gastrointestinal tract or the emergence of acid reflux, which is manifested in the symptom of bitter mouth. 2. Violent cough: violent cough can stimulate the throat to produce nausea and vomiting and other symptoms, resulting in increased pressure in the abdominal cavity, resulting in bile reflux into the stomach caused by bitter mouth. 3. Other: If coughing is accompanied by the presence of certain digestive disorders, it can also be manifested as a bitter mouth, such as acute and chronic gastroenteritis, chronic cholecystitis, and so on. Cough infusion mouth bitter may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or treatment.