Recognizing the causes closely related to epilepsy

  Epilepsy, commonly known as “crohn’s disease” or “sheep epilepsy”, is a chronic disease in which sudden abnormal discharges of neurons in the brain cause transient brain dysfunction. The clinical manifestations of epileptic seizures are complex and varied due to the different starting sites and transmission of abnormal discharges, which can manifest as seizure disorders of motor, sensory, autonomic, consciousness and mental disorders. The causes of epilepsy are diverse. After regular antiepileptic drug treatment, about 70% of patients with epilepsy can have their seizures controlled, and 50% to 60% of them can be cured after 2-5 years of treatment, and patients can work and live like normal people. According to the latest epidemiological data in China, the overall prevalence of epilepsy in China is 7.0‰, the annual incidence rate is 28.8/100,000, and the prevalence of active epilepsy with seizures within 1 year is 4.6‰. Accordingly, it is estimated that there are about 9 million epilepsy patients in China, of which 5-6 million are active epilepsy patients, while about 400,000 new epilepsy patients are added every year. Epilepsy has become the second most common disease after headache in neurology in China.    The main causes of epilepsy are as follows: 1, genetic; 2, craniocerebral trauma; 3, brain tumor; 4, craniocerebral surgery; 5, intracranial infection; 6, cerebrovascular disease; 7, prenatal and intrapartum injury; 8, metabolic disorders; 9, poisoning; 10, hypoxia; 11, congenital disorders; 12, hereditary disorders; 13, demyelinating disorders.  The seizure classification is currently commonly used is the seizure classification scheme proposed by the International League Against Epilepsy in 1981. The seizures are classified as partial/focal seizures, generalized seizures, and seizures that cannot be classified. 2010, the International League Against Epilepsy proposed an updated seizure classification scheme, and the new scheme reclassified and supplemented the seizures. The new scheme is more comprehensive and complete, although it summarizes the advances in epileptology research in recent years.